![]() With low levels of serotonin you’ll experience the worry-type of anxiety with ruminations, obsessing, panic attacks, insomnia (often lying awake worrying). He talks about the type of cell in the gut that produces serotonin – the enterochromaffin cell – and the fact that “ spore forming bacteria are some of the best stimulators of the enterochromaffin cell to produce serotonin.” He reminds us about the gut-brain connection and how anxiety and mental health issues come from the gut “ because the vast majority of serotonin in your body – more than ninety percent of it – is actually produced in the gut” and not in the brain. coagulans MTCC 5856 as an important new treatment option for major depressive disorder in IBS patients.ĭuring The Anxiety Summit 5: Gut-Brain Axis, I interviewed Kiran Krishnan who is a microbiologist, one of the founders of Microbiome Labs and a co-creator of MegaSporeBiotic™. The improvement in depression and IBS symptoms was statistically significant and clinically meaningful. It was a randomised, double-blind, placebo controlled, multi-centre, pilot clinical study and: In one study, Bacillus coagulans (one of the spore-forming strains in MegaSporeBiotic™), when used alone was shown to help ease depression and gut problems in IBS patients. Pretreatment with probiotic spore-forming Bacillus strains and a supplement of amino acids in combination with immunoglobulins exhibited anti-inflammatory and antioxidant effects in an AA-induced rat model of ulcerative colitis.
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